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JI-101

VEGFR2/PDGFR??/EphB4 抑制剂

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产品目录号: A13545

库存状态:中国现货中国现货

产品名 目录号 价格 数量
JI-101 5mg A13545-5
¥ 3,500.00
JI-101 10mg A13545-10
¥ 6,000.00
JI-101 25mg A13545-25
¥ 12,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.

JI-101

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Chemical Information

目录号 A13545
Mechanism of action Inhibitor
分子量 466.3305
化学分子式 C22H20BrN5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 900573-88-8
Synonyms JI 101, JI101
SMILES code COC1=C(C=C(C=C1)Br)NC(=O)NC2=CC=CC3=C2C=CN3CC4=CC(=NC=C4)N
化学名称 1-(1-((2-aminopyridin-4-yl)methyl)-1H-indol-4-yl)-3-(5-bromo-2-methoxyphenyl)urea.

生物活性

Description
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor beta (PDGFRβ), and the ephrin B4 receptor B4 (EphB4) with potential antiangiogenic and antineoplastic activities.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.44 mL 107.22 mL 214.44mL
0.5 mM 4.29 mL 21.44 mL 42.89 mL
1 mM 2.14 mL 10.72 mL 21.44 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.3305. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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