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JMV 390-1是主要的神经降压素和神经调节素N降解酶的抑制剂（内肽酶24.15，内肽酶24.11，亮氨酸氨基肽酶和内肽酶24.16的IC50值分别为31、40、52和58 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.24 mL | 111.22 mL | 222.45 mL |
| 0.5 mM | 4.45 mL | 22.24 mL | 44.49 mL |
| 1 mM | 2.22 mL | 11.12 mL | 22.24 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
*The above data is based on the productmolecular weight 449.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16026 |
|---|---|
| M. Wt | 449.54 |
| Formula | C23H35N3O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 148473-36-3 |
| Synonyms | JMV-390-1 |
| SMILES | O=C([C@H]([C@@H](C)CC)NC([C@@H](CC(NO)=O)CC1=CC=CC=C1)=O)N[C@H](C(O)=O)CC(C)C |
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