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JNJ-10229570

JNJ-10229570

Name: JNJ-10229570
SKU: A16876

目录号: A16876

MC1R and MC5R 拮抗剂

JNJ-10229570 Chemical Structure

CAS NO. 524923-88-4

JNJ-10229570是一种新型MC1R和MC5R拮抗剂，用于治疗原代人皮脂细胞。其抑制125I-NDP-α-MSH和人类细胞中MC1R和MC5R结合的IC50值分别为 270 nM 和 200 nM。

库存：现货

规格	价格	数量
2 mg	￥ 1,600.00
5 mg	￥ 3,200.00
10 mg	￥ 4,800.00
50 mg	￥ 14,000.00

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生物活性

JNJ-10229570是一种新型MC1R和MC5R拮抗剂，用于治疗原代人皮脂细胞。其抑制125I-NDP-α-MSH和人类细胞中MC1R和MC5R结合的IC50值分别为 270 nM 和 200 nM。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.68 mL	128.38 mL	256.76 mL
0.5 mM	5.14 mL	25.68 mL	51.35 mL
1 mM	2.57 mL	12.84 mL	25.68 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 389.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16876
作用机制	Antagonist (拮抗剂)
M. Wt	389.47
Formula	C22H19N3O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	524923-88-4
Synonyms	JNJ10229570, JNJ 10229570, UNII-N9IX402L35
SMILES	COC1=CC=CC=C1C2=N/C(SN2C3=CC=CC=C3OC)=N\C4=CC=CC=C4