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JNJ-10397049是orexin-2受体（OX2R）的有效，选择性且可生物利用的拮抗剂（OX2R的KB = 4.5 nM，OX1R的1.1μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.65 mL | 103.26 mL | 206.53 mL |
| 0.5 mM | 4.13 mL | 20.65 mL | 41.31 mL |
| 1 mM | 2.07 mL | 10.33 mL | 20.65 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.13 mL |
*The above data is based on the productmolecular weight 484.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14104 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 484.2 |
| Formula | C19H20Br2N2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 708275-58-5 |
| Synonyms | JNJ 10397049, JNJ10397049 |
| SMILES | CC1(OC[C@@H]([C@@H](O1)C2=CC=CC=C2)NC(=O)NC3=C(C=C(C=C3)Br)Br)C |
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