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HDAC 抑制剂

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产品目录号: A10492


产品名 目录号 价格 数量
JNJ-26481585 5mg A10492-5
¥ 1,100.00
JNJ-26481585 10mg A10492-10
¥ 2,000.00
JNJ-26481585 50mg A10492-50
¥ 4,000.00
JNJ-26481585 100mg A10492-100
¥ 6,200.00
JNJ-26481585 10mM * 1mL in DMSO A10492-10mM-D
¥ 1,200.00



JNJ-26481585 is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 JNJ-26481585 发表的文献 (1)
  • Minoru Ueda, .et al. The Distinct Roles of Class I and II RPD3-Like Histone Deacetylases in Salinity Stress Response, Plant Physiol, 2017, Dec; 175(4): 1760每1773 PMID: 29018096

Chemical Information

目录号 A10492
Mechanism of action Inhibitor
分子量 394.5
化学分子式 C21H26N6O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 875320-29-9
Synonyms JNJ26481585
化学名称 N-hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)methyl)piperidin-1-yl)pyrimidine-5-carboxamide


JNJ-26481585 is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).


Solubility (25°C) * In vitro DMSO 79 mg/mL (200.26 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.74 mL 253.49mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.53 mL 12.67 mL 25.35 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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