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JNJ 26854165


p53 activator

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产品目录号: A10491


产品名 目录号 价格 数量
JNJ 26854165 5mg A10491-5
¥ 500.00
JNJ 26854165 10mg A10491-10
¥ 900.00
JNJ 26854165 50mg A10491-50
¥ 3,800.00
JNJ 26854165 100mg A10491-100
¥ 5,600.00
JNJ 26854165 10mM * 1mL in DMSO A10491-10mM-D
¥ 920.00



JNJ-26854165 is one of p53-activating agents and synergizes with AraC or doxorubicin to induce p53-mediated apoptosis and may provide a novel therapeutic approach for the treatment of acute leukemias.

JNJ 26854165




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 JNJ 26854165 发表的文献 (1)
  • Chang SJ, .et al. Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma, Arch Biochem Biophys, 2018, Jun 1;647:10-32 PMID: 29655550

Chemical Information

目录号 A10491
Mechanism of action Activator
分子量 328.4
化学分子式 C21H20N4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 881202-45-5
Synonyms JNJ26854165, JNJ-26854165
化学名称 N-[2-(1H-Indol-3-yl)ethyl]-N'-(4-pyridinyl)-1,4-benzenediamine


JNJ-26854165 is one of p53-activating agents and synergizes with AraC or doxorubicin to induce p53-mediated apoptosis and may provide a novel therapeutic approach for the treatment of acute leukemias.


Solubility (25°C) * In vitro DMSO 66 mg/mL (200.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (6.08 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.45 mL 152.25 mL 304.51mL
0.5 mM 6.09 mL 30.45 mL 60.9 mL
1 mM 3.05 mL 15.23 mL 30.45 mL
5 mM 0.61 mL 3.05 mL 6.09 mL

*The above data is based on the productmolecular weight 328.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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