JNJ-28312141

目录号: A12687

CSF1R inhibitor

JNJ-28312141 Chemical Structure

CAS NO. 885692-52-4

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
25 mg
¥ 12,000.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.56 mL 217.12 mL
0.5 mM 4.34 mL 21.71 mL 43.42 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12687
MECHANISM OF ACTION Inhibitor
M. Wt 460.57
Formula C26H32N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 885692-52-4
Synonyms JNJ 28312141, JNJ28312141
SMILES CN(C)CC(=O)N1CCC(CC1)C2=CC(=C(C=C2)NC(=O)C3=NC=C(N3)C#N)C4=CCCCC4

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 JNJ-28312141 | JNJ-28312141 供应商 | 订购 JNJ-28312141 | JNJ-28312141 价格 | JNJ-28312141 生产商 | 订单 JNJ-28312141 | JNJ-28312141 代理商 | 购买 885692-52-4| 885692-52-4 供应商 | 订购 885692-52-4 | 885692-52-4 价格 | 885692-52-4 生产商 | 订单 885692-52-4 | 885692-52-4 代理商|buy JNJ-28312141 | JNJ-28312141 Supplier | purchase JNJ-28312141 | JNJ-28312141 cost | JNJ-28312141 manufacturer | order JNJ-28312141 | JNJ-28312141 distributor | buy 885692-52-4| 885692-52-4 Supplier | purchase 885692-52-4 | 885692-52-4 cost | 885692-52-4 manufacturer | order 885692-52-4 | 885692-52-4 distributor
Rewards