JNJ-38158471
目录号: A22345
VEGFR-2 抑制剂
JNJ-38158471 是一种耐受性好、可口服、高度选择性的 VEGFR-2 抑制剂,其 IC50 为 40 nM。JNJ-38158471 还分别以 IC50 为 180 nM 和 500 nM 抑制 Ret 和 Kit。
Discription | JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor, with an IC50 of 40 nM. JNJ-38158471 also inhibits Ret and Kit with IC50s of 180 and 500 nM, respectively. |
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目录号 | A22345 |
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分子式 | C15H17ClN6O3 |
分子量 | 364.79 |
CAS号 | 951151-97-6 |
SMILES | O=C(NCC)NC1=CC=C(OC2=NC=NC(N)=C2/C=N/OC)C=C1Cl |
其他名称 | JNJ38158471;JNJ 38158471 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2