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JNJ-5207852 is a selective and potent histamine H3 receptor (H3R) antagonist, with pKis of 8.9, 9.24 for rat and human H3R, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.6 mL | 157.99 mL | 315.98 mL |
| 0.5 mM | 6.32 mL | 31.6 mL | 63.2 mL |
| 1 mM | 3.16 mL | 15.8 mL | 31.6 mL |
| 5 mM | 0.63 mL | 3.16 mL | 6.32 mL |
*The above data is based on the productmolecular weight 316.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21480 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 316.48 |
| Formula | C20H32N2O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 398473-34-2 |
| Synonyms | JNJ5207852, JNJ 5207852 |
| SMILES | N1(CCCOC2=CC=C(CN3CCCCC3)C=C2)CCCCC1 |
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