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JNJ-54175446

目录号: A18675
P2X7 receptor 拮抗剂
JNJ-54175446 是一种强效且选择性的能穿透大脑的 P2X7 受体拮抗剂,对人类P2X7受体(hP2X7 receptor)和大鼠P2X7受体(rP2X7 receptor)的 pIC50 分别为 8.46 和 8.81。
Grouped product items
规格 价格 库存 数量
1mg
¥1,995.00
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5mg
¥5,005.00
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10mg
¥6,860.00
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25mg
¥10,605.00
现货
50mg
¥13,825.00
现货
100mg
¥19,285.00
现货
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生物活性
Discription JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.
产品信息
目录号 A18675
分子式 C18H13ClF4N6O
分子量 440.78
CAS号 1627902-21-9
SMILES ClC1=C(C=CC=C1C(N2CCC3=C(N=NN3C4=NC=C(F)C=N4)[C@H]2C)=O)C(F)(F)F
其他名称 JNJ54175446, JNJ 54175446
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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