JNJ-61432059

Name: JNJ-61432059
SKU: A20209

目录号: A20209

AMPAR negative modulator

JNJ-61432059 Chemical Structure

CAS NO. 2035814-50-5

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8.

库存：现货

规格	价格	数量
5 mg	￥ 4,200.00
10 mg	￥ 7,200.00
50 mg	￥ 21,000.00

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产品详情

生物活性

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.55 mL	112.75 mL	225.49 mL
0.5 mM	4.51 mL	22.55 mL	45.1 mL
1 mM	2.25 mL	11.27 mL	22.55 mL
5 mM	0.45 mL	2.25 mL	4.51 mL

*The above data is based on the productmolecular weight 443.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20209
作用机制	Modulator (调节剂)
M. Wt	443.47
Formula	C25H22FN5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2035814-50-5
Synonyms	JNJ 61432059; JNJ61432059
SMILES	OC1CCN(C2=NC=CC3=C(C4=CC=C(NC(C5)=O)C5=C4)C(C6=CC=C(F)C=C6)=NN32)CC1