JNJ-64619178

目录号: A16861

Histone Methyltransferase 抑制剂

JNJ-64619178

JNJ-64619178 Chemical Structure

CAS NO. 2086772-26-9

JNJ-64619178是PRMT5抑制剂,在不同的体外和细胞条件下均具有高选择性和强效性(亚纳摩尔范围,PRMT5-MEP-50 IC50 = 0.14 nM),并具有良好的药代动力学和安全性。

库存: 现货

规格 价格 数量
1 mg
¥ 900.00
2 mg
¥ 1,400.00
5 mg
¥ 2,000.00
50 mg
¥ 10,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

JNJ-64619178是PRMT5抑制剂,在不同的体外和细胞条件下均具有高选择性和强效性(亚纳摩尔范围,PRMT5-MEP-50 IC50 = 0.14 nM),并具有良好的药代动力学和安全性。
In vitro DMSO 94 mg/mL (194.47 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.69 mL 103.44 mL 206.88 mL
0.5 mM 4.14 mL 20.69 mL 41.38 mL
1 mM 2.07 mL 10.34 mL 20.69 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 483.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16861
作用机制 Inhibitor (抑制剂)
M. Wt 483.37
Formula C22H23BrN6O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 2086772-26-9
Synonyms JNJ64619178, JNJ 64619178
SMILES BrC1=C(N)N=C(C=C(CC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(N=CN=C4N)=C4C=C3)C2)C=C5)C5=C1

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