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JNK-IN-8

目录号: A12749
JNK 抑制剂
JNK-IN-8 是首个针对 JNK1JNK2JNK4 的不可逆 JNK 抑制剂,其 IC50 分别为 4.7 nM、18.7 nM 和 1 nM。
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规格 价格 库存 数量
2mg
¥210.00
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5mg
¥455.00
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10mg
¥805.00
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25mg
¥1,470.00
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50mg
¥2,485.00
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100mg
¥3,710.00
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200mg
¥5,285.00
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10mM * 1mL in DMSO
¥490.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用JNK-IN-8发表的1篇文献
  • Mark P Roberto, .et al. , Immunity, 2021, Aug 10;54(8):1807-1824.e14 PMID: 34380064
  • 生物活性
    Discription JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A12749
    分子式 C29H29N7O2
    分子量 507.59
    CAS号 1410880-22-6
    SMILES CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)/C=C/CN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO Warmed: 91 mg/mL (179.27 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.7 mL 98.5 mL 197.01 mL
    0.5 mM 3.94 mL 19.7 mL 39.4 mL
    1 mM 1.97 mL 9.85 mL 19.7 mL
    5 mM 0.39 mL 1.97 mL 3.94 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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