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BET 抑制剂

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产品目录号: A12729


产品名 目录号 价格 数量
(+)-JQ1 5mg A12729-5
¥ 700.00
(+)-JQ1 10mg A12729-10
¥ 900.00
(+)-JQ1 25mg A12729-25
¥ 1,500.00
(+)-JQ1 50mg A12729-50
¥ 2,400.00
(+)-JQ1 10mM * 1mL in DMSO A12729-10mM-D
¥ 1,320.00



(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 (+)-JQ1 发表的文献 (2)
  • A Carrer, .et al. Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis, Cancer Discov, 2019, Jan 9. pii: CD-18-0567 PMID: 30626590
  • Clocchiatti A, .et al. Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation, J Clin Invest, 2018, Dec 3;128(12):5531-5548 PMID: 30395538

Chemical Information

目录号 A12729
Mechanism of action Inhibitor
分子量 456.99
化学分子式 C23H25ClN4O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1268524-70-4
Synonyms N/A
SMILES code CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
化学名称 (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester


(+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor.


Solubility (25°C)* In vitro DMSO 91 mg/mL (199.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol 91 mg/mL (199.12 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.88 mL 109.41 mL 218.82mL
0.5 mM 4.38 mL 21.88 mL 43.76 mL
1 mM 2.19 mL 10.94 mL 21.88 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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