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JTE-013 is a potent and specific S1P2 (Sphingosine-1-Phosphate 2; EDG-5) antagonist. JTE-013 inhibits the specific binding of radiolabeled S1P to human and rat S1P2 with IC50s of 17 nM and 22 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.49 mL | 122.46 mL | 244.92 mL |
| 0.5 mM | 4.9 mL | 24.49 mL | 48.98 mL |
| 1 mM | 2.45 mL | 12.25 mL | 24.49 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.9 mL |
*The above data is based on the productmolecular weight 408.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22583 |
|---|---|
| M. Wt | 408.29 |
| Formula | C17H19Cl2N7O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 383150-41-2 |
| SMILES | CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C |
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