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JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.51 mL | 82.53 mL | 165.06 mL |
| 0.5 mM | 3.3 mL | 16.51 mL | 33.01 mL |
| 1 mM | 1.65 mL | 8.25 mL | 16.51 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.3 mL |
*The above data is based on the productmolecular weight 605.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20776 |
|---|---|
| M. Wt | 605.85 |
| Formula | C34H43N3O3S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 776309-04-7 |
| Synonyms | JTT551, JTT-551 |
| SMILES | O=C(O)CN(CC1=NC=C(C(C)(C)C)S1)CC2=NC(C3=CC=C(COC4=CC=C(C(CCC)CCC)C=C4)C=C3)=CS2 |
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