JZL184

目录号: A12747

MAGL 抑制剂

JZL184

JZL184 Chemical Structure

CAS NO. 1101854-58-3

JZL184是一种有效的选择性单酰基甘油脂肪酶(MAGL)抑制剂。体内阻断内源性大麻素2-花生四烯酸甘油酯(2-AG)的水解(IC50 = 8 nM)。

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
25 mg
¥ 800.00
50 mg
¥ 1,300.00
100 mg
¥ 2,000.00
10mM * 1mL in DMSO
¥ 610.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

JZL184是一种有效的选择性单酰基甘油脂肪酶(MAGL)抑制剂。体内阻断内源性大麻素2-花生四烯酸甘油酯(2-AG)的水解(IC50 = 8 nM)。
In vitro (25°C) DMSO 86 mg/mL (165.22 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+40%PEG300+5%Tween80+ddH2O 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.21 mL 96.06 mL 192.13 mL
0.5 mM 3.84 mL 19.21 mL 38.43 mL
1 mM 1.92 mL 9.61 mL 19.21 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12747
作用机制 Inhibitor (抑制剂)
M. Wt 520.49
Formula C27H24N2O9
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1101854-58-3
Synonyms JZL-184, JZL 184
SMILES C1CN(CCC1C(C2=CC3=C(C=C2)OCO3)(C4=CC5=C(C=C4)OCO5)O)C(=O)OC6=CC=C(C=C6)[N+](=O)[O-]

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