K-Ras(G12C) inhibitor 6
目录号: A14103
K-Ras(G12C) 抑制剂
K-Ras(G12C)抑制剂6是一种不可逆的肿瘤基因K-Ras(G12C)抑制剂,它改变了原生核苷酸的偏好,使其更倾向于选择GDP而非GTP。
Discription | K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP. |
---|
目录号 | A14103 |
---|---|
分子式 | C17H22Cl2N2O3S |
分子量 | 405.34 |
CAS号 | 2060530-16-5 |
SMILES | C1CN(CCC1NC(=O)CCCS)C(=O)COC2=C(C=C(C=C2)Cl)Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 75 mg/mL (185.03 mM) | |
Water | Insoluble | ||
Ethanol | 28 mg/mL (69.08 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.67 mL | 123.35 mL | 246.71 mL |
0.5 mM | 4.93 mL | 24.67 mL | 49.34 mL |
1 mM | 2.47 mL | 12.34 mL | 24.67 mL |
5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2