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BMP 抑制剂

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产品目录号: A14311


产品名 目录号 价格 数量
K02288 10mg A14311-10
¥ 700.00
K02288 25mg A14311-25
¥ 1,200.00
K02288 50mg A14311-50
¥ 2,000.00
K02288 10mM * 1mL in DMSO A14311-10mM-D
¥ 850.00



K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14311
Mechanism of action Inhibitor
分子量 352.38
化学分子式 C20H20N2O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1431985-92-0
Synonyms K 02288, K-02288
化学名称 3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol


K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6.
Target Value
ALK2IC50: 1.1nM
ALK1IC50: 1.8nM
ALK6IC50: 6.4nM
ALK3IC50: 34.4nM
ALK4IC50: 302nM
ALK5IC50: 321nM


Solubility (25°C)* In vitro DMSO 70 mg/mL (198.64 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.38 mL 141.89 mL 283.78mL
0.5 mM 5.68 mL 28.38 mL 56.76 mL
1 mM 2.84 mL 14.19 mL 28.38 mL
5 mM 0.57 mL 2.84 mL 5.68 mL

*The above data is based on the productmolecular weight 352.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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