K03861

目录号: A15889

CDK inhibitor

K03861

K03861 Chemical Structure

CAS NO. 853299-07-7

K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

库存: 现货

规格 价格 数量
5 mg
¥ 1,400.00
10 mg
¥ 2,200.00
25 mg
¥ 4,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
Targets
CDK2(C118L/A144C) CDK2(A144C) CDK2(C118L) CDK2(WT)
9.7 nM(Kd)15.4 nM(Kd)18.6 nM(Kd)50 nM(Kd)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15889
MECHANISM OF ACTION Inhibitor
M. Wt 501.5
Formula C24H26F3N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 853299-07-7
Synonyms K 03861, K-03861
SMILES CN1CCN(CC2=C(C(F)(F)F)C=C(/N=C(O)/NC3=CC=C(OC(C=CN4)=NC4=N)C=C3)C=C2)CC1

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