K03861
目录号: A15889
CDK 抑制剂
K03861 是一种 II 型 CDK2 抑制剂，其 Kd 分别为 CDK2(WT) 50 nM、CDK2(C118L) 18.6 nM、CDK2(A144C) 15.4 nM 和 CDK2(C118L/A144C) 9.7 nM。
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生物活性
| Discription | K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. | ||
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| Targets |
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产品信息
| 目录号 | A15889 |
|---|---|
| 分子式 | C24H26F3N7O2 |
| 分子量 | 501.5 |
| CAS号 | 853299-07-7 |
| SMILES | CN1CCN(CC2=C(C(F)(F)F)C=C(/N=C(O)/NC3=CC=C(OC(C=CN4)=NC4=N)C=C3)C=C2)CC1 |
| 其他名称 | K 03861, K-03861 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 97 mg/mL (193.42 mM) | |
| Water | Insoluble | ||
| Ethanol | 15 mg/mL (29.91 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.94 mL | 99.7 mL | 199.4 mL |
| 0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 853299-07-7 | 853299-07-7 供应商 | 853299-07-7 花费 | 853299-07-7 生产商 | 订购 853299-07-7 | 853299-07-7 代理商