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SphK2 抑制剂

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产品目录号: A16288


产品名 目录号 价格 数量
K145 5mg A16288-5
¥ 600.00
K145 10mg A16288-10
¥ 1,000.00
K145 50mg A16288-50
¥ 3,200.00



K145 is a selective SphK2 inhibitor with an IC50 of 4.30± 0.06 μM , while no inhibition of SphK1 at concentrations up to 10 uM.





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Chemical Information

目录号 A16288
Mechanism of action Inhibitor
分子量 348.46
化学分子式 C18H24N2O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1309444-75-4
Synonyms SphK2 inhibitor, K 145, K-145
化学名称 (5Z)-3-(2-aminoethyl)-5-[3-(4-butoxyphenyl)propylidene]-1,3-thiazolidine-2,4-dione


K145 is a selective SphK2 inhibitor with an IC50 of 4.30± 0.06 μM , while no inhibition of SphK1 at concentrations up to 10 uM.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.7 mL 143.49 mL 286.98mL
0.5 mM 5.74 mL 28.7 mL 57.4 mL
1 mM 2.87 mL 14.35 mL 28.7 mL
5 mM 0.57 mL 2.87 mL 5.74 mL

*The above data is based on the productmolecular weight 348.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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