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KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has antitumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.02 mL | 90.09 mL | 180.17 mL |
| 0.5 mM | 3.6 mL | 18.02 mL | 36.03 mL |
| 1 mM | 1.8 mL | 9.01 mL | 18.02 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
*The above data is based on the productmolecular weight 555.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20111 |
|---|---|
| M. Wt | 555.03 |
| Formula | C32H23ClN8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1380088-03-8 |
| SMILES | NC1=C2C(N(C3=CC=CC(C4=CN=NN4CC5=CC(C6=CC=CC=C6)=CC=C5)=C3)N=C2C7=CC=C(Cl)C=C7)=NC=N1 |
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