KC7F2

目录号: A15359

HIF 抑制剂

KC7F2

KC7F2 Chemical Structure

CAS NO. 927822-86-4

KC7F2是HIF-1α蛋白翻译的抑制剂,但不是转录的抑制剂,可抑制蛋白质合成的两个关键调节子,即真核翻译起始因子4E结合蛋白1(4EBP1)和p70 S6激酶(S6K)的磷酸化。

库存: 现货

规格 价格 数量
10 mg
¥ 550.00
50 mg
¥ 1,900.00
100 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

KC7F2是HIF-1α蛋白翻译的抑制剂,但不是转录的抑制剂,可抑制蛋白质合成的两个关键调节子,即真核翻译起始因子4E结合蛋白1(4EBP1)和p70 S6激酶(S6K)的磷酸化。
靶点信息
HIF-1α
20 μM
In vitro DMSO 94 mg/mL (164.8 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.53 mL 87.66 mL 175.32 mL
0.5 mM 3.51 mL 17.53 mL 35.06 mL
1 mM 1.75 mL 8.77 mL 17.53 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 570.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15359
作用机制 Inhibitor (抑制剂)
M. Wt 570.38
Formula C16H16Cl4N2O4S4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 927822-86-4
SMILES C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl

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