KC7F2
目录号: A15359
HIF 抑制剂
KC7F2 是一种抑制 HIF-1α 蛋白质翻译（而非转录）的抑制剂，它抑制了两个蛋白质合成关键调节因子的磷酸化，这两个因子分别是 真核翻译起始因子4E结合蛋白1（4EBP1）和 p70 S6 激酶（S6K）。
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生物活性
| Discription | KC7F2 is an inhibitor of HIF-1α protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K). | ||
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| Targets |
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产品信息
| 目录号 | A15359 |
|---|---|
| 分子式 | C16H16Cl4N2O4S4 |
| 分子量 | 570.38 |
| CAS号 | 927822-86-4 |
| SMILES | C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 94 mg/mL (164.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.53 mL | 87.66 mL | 175.32 mL |
| 0.5 mM | 3.51 mL | 17.53 mL | 35.06 mL |
| 1 mM | 1.75 mL | 8.77 mL | 17.53 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 927822-86-4 | 927822-86-4 供应商 | 927822-86-4 花费 | 927822-86-4 生产商 | 订购 927822-86-4 | 927822-86-4 代理商