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KDU691

产品详情

生物活性

KDU691是疟原虫PI4K抑制剂（分别针对次生孢子形式和肝裂殖体的IC 50值为0.18μM和0.061μM）。

溶解度 *

In vitro	DMSO	76 mg/mL (181.01 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (21.43 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.82 mL	119.09 mL	238.17 mL
0.5 mM	4.76 mL	23.82 mL	47.63 mL
1 mM	2.38 mL	11.91 mL	23.82 mL
5 mM	0.48 mL	2.38 mL	4.76 mL

*The above data is based on the productmolecular weight 419.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17066
作用机制	Inhibitor (抑制剂)
M. Wt	419.86
Formula	C22H18ClN5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1513879-19-0
Synonyms	KDU 691, KDU-691
SMILES	ClC1=CC=C(N(C(C2=CN3C(C=N2)=NC=C3C4=CC=C(C(NC)=O)C=C4)=O)C)C=C1