Ki16425
Ki16425 是一种 LPA 受体拮抗剂,对 LPA1 和 LPA3 有选择性,其对人类 LPA1、LPA2 和 LPA3 受体的 Ki 值分别为 0.34、6.5 和 0.93 微米。
| Discription | Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3 and exhibits Ki values of 0.34, 6.5, and 0.93 μM for the human LPA1, LPA2, and LPA3 receptors, respectively. |
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| 目录号 | A10501 |
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| 分子式 | C23H23ClN2O5S |
| 分子量 | 475 |
| CAS号 | 355025-24-0 |
| SMILES | CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)O |
| 其他名称 | Ki-16425 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 85 mg/mL (178.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 85 mg/mL (178.96 mM) | ||
| In vivo | 5% DMSO+95% Corn oil | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.05 mL | 105.26 mL | 210.53 mL |
| 0.5 mM | 4.21 mL | 21.05 mL | 42.11 mL |
| 1 mM | 2.11 mL | 10.53 mL | 21.05 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.21 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2