KIN001-051
目录号: A16923
Lck 抑制剂
KIN001-051 是一种强效且选择性的 lck 抑制剂。淋巴细胞特异性蛋白酪氨酸激酶(Lck)是 Src 家族非受体蛋白酪氨酸激酶的成员之一,它在 T 细胞受体信号传导的初始步骤中发挥关键作用,这些信号传导触发细胞因子的产生。
| Discription | KIN001-051 is a potent and selective inhibitor of lck. Lymphocyte-speci?c protein tyrosine kinase (Lck) is a member of the Src-family of non-receptor protein tyrosine kinases and plays a critical role in the initial steps of T cell receptor signaling that trigger the production of cytokines. | |||||
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| Cell Research |
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| 目录号 | A16923 |
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| 分子式 | C23H22N4O |
| 分子量 | 370.46 |
| CAS号 | 213743-31-8 |
| SMILES | NC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1 |
| 其他名称 | KIN001051, KIN001 051 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 18 mg/mL (48.58 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (10.79 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.99 mL | 134.97 mL | 269.93 mL |
| 0.5 mM | 5.4 mL | 26.99 mL | 53.99 mL |
| 1 mM | 2.7 mL | 13.5 mL | 26.99 mL |
| 5 mM | 0.54 mL | 2.7 mL | 5.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2