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KIRA6

KIRA6

Name: KIRA6
SKU: A12516

目录号: A12516

IRE1α RNase kinase inhibitor

KIRA6 Chemical Structure

CAS NO. 1589527-65-0

KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 ?M. KIRA6 can trigger an apoptotic response.

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,550.00
50 mg	￥ 4,600.00
100 mg	￥ 9,200.00

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生物活性

KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 ?M. KIRA6 can trigger an apoptotic response.

溶解度 *

In vitro	DMSO	59 mg/mL (113.78 mM)
	Water	Insoluble
	Ethanol	59 mg/mL (113.78 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.29 mL	96.43 mL	192.85 mL
0.5 mM	3.86 mL	19.29 mL	38.57 mL
1 mM	1.93 mL	9.64 mL	19.29 mL
5 mM	0.39 mL	1.93 mL	3.86 mL

*The above data is based on the productmolecular weight 518.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12516
作用机制	Inhibitor (抑制剂)
M. Wt	518.53
Formula	C28H25F3N6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1589527-65-0
Synonyms	KIRA-6
SMILES	O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=C3C=CC=CC3=C(C4=C5C(N)=NC=CN5C(C(C)(C)C)=N4)C=C2