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Kira8 Hydrochloride

Kira8 Hydrochloride

Name: Kira8 Hydrochloride
SKU: A21780

目录号: A21780

IRE1α inhibitor

Kira8 Hydrochloride Chemical Structure

CAS NO. 2250019-92-0

Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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生物活性

Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.68 mL	78.42 mL	156.84 mL
0.5 mM	3.14 mL	15.68 mL	31.37 mL
1 mM	1.57 mL	7.84 mL	15.68 mL
5 mM	0.31 mL	1.57 mL	3.14 mL

*The above data is based on the productmolecular weight 637.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21780
作用机制	Inhibitor (抑制剂)
M. Wt	637.58
Formula	C31H30Cl2N6O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2250019-92-0
Synonyms	AMG-18 Hydrochloride, AMG18, AMG 18; Kira-8, Kira 8
SMILES	O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(C3=CC=C2)OC4=NC=CC=C4C5=NC(N[C@H]6CNCCC6)=NC=C5)=O.[H]Cl