|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||25.95 mL||129.75 mL||259.49 mL|
|0.5 mM||5.19 mL||25.95 mL||51.9 mL|
|1 mM||2.59 mL||12.97 mL||25.95 mL|
|5 mM||0.52 mL||2.59 mL||5.19 mL|
*The above data is based on the productmolecular weight 385.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nmol/L. It is highly selective for PERK with IC(50)…
ISRIB (trans-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects…
GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.