KL-1
目录号: A18418
SEC 抑制剂
KL-1 是一种抑制剂，它能够抑制 SEC 和 Pol II 的转录延伸，通过破坏 SEC 内的 cyclin T1-AFF4 互动，减弱 SEC 依赖的快速转录反应。KL-1 抑制 MYC 转录程序。
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生物活性
| Discription | KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs. |
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产品信息
| 目录号 | A18418 |
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| 分子式 | C18H16ClNO4 |
| 分子量 | 345.78 |
| CAS号 | 900308-84-1 |
| SMILES | O=C(NC1=CC(Cl)=CC=C1C)C(CC(C2=CC=CC(OC)=C2)=O)=O |
| 其他名称 | KL1; KL 1; KL-1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 64 mg/mL (185.08 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.92 mL | 144.6 mL | 289.2 mL |
| 0.5 mM | 5.78 mL | 28.92 mL | 57.84 mL |
| 1 mM | 2.89 mL | 14.46 mL | 28.92 mL |
| 5 mM | 0.58 mL | 2.89 mL | 5.78 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 900308-84-1 | 900308-84-1 供应商 | 900308-84-1 花费 | 900308-84-1 生产商 | 订购 900308-84-1 | 900308-84-1 代理商