KM 11060
目录号: A15843
F508del-CFTR trafficking corrector
KM 11060 纠正 F508del-CFTR 的运输问题，增加了功能性 CFTR 在细胞膜上的数量（约 75%）并且 抑制 PDE5 活性。
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生物活性
| Discription | KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity |
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产品信息
| 目录号 | A15843 |
|---|---|
| 分子式 | C19H17Cl2N3O2S |
| 分子量 | 422.33 |
| CAS号 | 774549-97-2 |
| SMILES | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O |
| 其他名称 | KM-11060, KM11060 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 81 mg/mL (191.79 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (4.73 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.68 mL | 118.39 mL | 236.78 mL |
| 0.5 mM | 4.74 mL | 23.68 mL | 47.36 mL |
| 1 mM | 2.37 mL | 11.84 mL | 23.68 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 774549-97-2 | 774549-97-2 供应商 | 774549-97-2 花费 | 774549-97-2 生产商 | 订购 774549-97-2 | 774549-97-2 代理商