(E)-KN-93 phosphate
KN-93 Phosphate 是一种强效且特异性的 Ca2+/钙调蛋白依赖性蛋白激酶 II (CaMKII) 抑制剂,其抑制常数 Ki 为 0.37 μM,对 APK、PKC、MLCK 或 Ca2+-PDE 的活性没有显著的抑制效果。
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重要通知:仅供研究使用。我们不向患者销售。
重要通知:仅供研究使用。我们不向患者销售。
| Discription | KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities. | ||
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| Targets |
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| 目录号 | A14288 |
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| 分子式 | C26H32ClN2O8PS |
| 分子量 | 599.03 |
| CAS号 | 1188890-41-6 |
| SMILES | CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O |
| 其他名称 | KN93, KN 93 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 86 mg/mL (143.56 mM) | |
| Water | 79 mg/mL (131.88 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.69 mL | 83.47 mL | 166.94 mL |
| 0.5 mM | 3.34 mL | 16.69 mL | 33.39 mL |
| 1 mM | 1.67 mL | 8.35 mL | 16.69 mL |
| 5 mM | 0.33 mL | 1.67 mL | 3.34 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2