KNK437

Name: KNK437
SKU: A14389
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A14389

pan-HSP 抑制剂

KNK437 在剂量依赖性的方式下抑制了 COLO 320DM（人类结肠癌细胞）中热耐受性的获得以及包括 HSP105、HSP70 和 HSP40 在内的各种热休克蛋白（HSPs）的诱导。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,085.00	现货
50mg	¥1,820.00	现货
100mg	¥3,500.00	现货
200mg	¥5,250.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

KNK437, dose-dependently inhibited the acquisition of thermotolerance and the induction of various HSPs including HSP105, HSP70, and HSP40 in COLO 320DM (human colon carcinoma) cells.

Targets

Target	Value

产品信息

目录号	A14389
分子式	C13H11NO4
分子量	245.23
CAS号	218924-25-5
SMILES	O=CN1C(/C(CC1)=C\C2=CC=C(OCO3)C3=C2)=O
其他名称	KNK-437, KNK 437
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 14 mg/mL (57.08 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.78 mL	203.89 mL	407.78 mL
0.5 mM	8.16 mL	40.78 mL	81.56 mL
1 mM	4.08 mL	20.39 mL	40.78 mL
5 mM	0.82 mL	4.08 mL	8.16 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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