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Ras-Raf interaction 抑制剂

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产品目录号: A13135


产品名 目录号 价格 数量
Kobe0065 10mg A13135-10
¥ 500.00
Kobe0065 25mg A13135-25
¥ 900.00
Kobe0065 50mg A13135-50
¥ 1,350.00



Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.





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Chemical Information

目录号 A13135
Mechanism of action Inhibitor
分子量 449.79
化学分子式 C15H11ClF3N5O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 436133-68-5
Synonyms Kobe-0065
SMILES code CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl
化学名称 N-(3-Chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide


Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
H-Ras-cRaf1 interaction


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.23 mL 111.16 mL 222.33mL
0.5 mM 4.45 mL 22.23 mL 44.47 mL
1 mM 2.22 mL 11.12 mL 22.23 mL
5 mM 0.44 mL 2.22 mL 4.45 mL

*The above data is based on the productmolecular weight 449.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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