Kobe0065
目录号: A13135
Ras-Raf interaction 抑制剂
Kobe0065 抑制锚定依赖性和非依赖性生长，阻断 MEK/ERK 活性，并在 H-rasG12V 转化的 NIH3T3 细胞中诱导凋亡。
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生物活性
| Discription | Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells. | ||
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产品信息
| 目录号 | A13135 |
|---|---|
| 分子式 | C15H11ClF3N5O4S |
| 分子量 | 449.79 |
| CAS号 | 436133-68-5 |
| SMILES | CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl |
| 其他名称 | Kobe-0065 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 85 mg/mL (188.98 mM) | |
| Water | Insoluble | ||
| Ethanol | 12 mg/mL (26.68 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.23 mL | 111.16 mL | 222.33 mL |
| 0.5 mM | 4.45 mL | 22.23 mL | 44.47 mL |
| 1 mM | 2.22 mL | 11.12 mL | 22.23 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 436133-68-5 | 436133-68-5 供应商 | 436133-68-5 花费 | 436133-68-5 生产商 | 订购 436133-68-5 | 436133-68-5 代理商