Kobe0065

目录号: A13135

Ras-Raf interaction 抑制剂

Kobe0065

Kobe0065 Chemical Structure

CAS NO. 436133-68-5

Kobe0065抑制锚定依赖性和非依赖性生长,阻断MEK / ERK活性并诱导H-rasG12V转化的NIH3T3细胞凋亡。

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 900.00
50 mg
¥ 1,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Kobe0065抑制锚定依赖性和非依赖性生长,阻断MEK / ERK活性并诱导H-rasG12V转化的NIH3T3细胞凋亡。
靶点信息
H-Ras-cRaf1 interaction
In vitro DMSO 85 mg/mL (188.98 mM)
Water Insoluble
Ethanol 12 mg/mL (26.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.23 mL 111.16 mL 222.33 mL
0.5 mM 4.45 mL 22.23 mL 44.47 mL
1 mM 2.22 mL 11.12 mL 22.23 mL
5 mM 0.44 mL 2.22 mL 4.45 mL

*The above data is based on the productmolecular weight 449.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13135
作用机制 Inhibitor (抑制剂)
M. Wt 449.79
Formula C15H11ClF3N5O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 436133-68-5
Synonyms Kobe-0065
SMILES CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl

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