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Kobe2602

Ras?€?Raf 抑制剂

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产品目录号: A12578

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Kobe2602 5mg A12578-5
¥ 1,500.00
Kobe2602 10mg A12578-10
¥ 2,500.00
Kobe2602 25mg A12578-25
¥ 4,500.00
Kobe2602 50mg A12578-50
¥ 8,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.

Kobe2602

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Chemical Information

目录号 A12578
Mechanism of action Inhibitor
分子量 419.31
化学分子式 C14H9F4N5O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 454453-49-7
Synonyms Kobe-2602
SMILES code C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F
化学名称 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide

生物活性

Description
Kobe2602 is an analog of Kobe0065. Exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.85 mL 119.24 mL 238.49mL
0.5 mM 4.77 mL 23.85 mL 47.7 mL
1 mM 2.38 mL 11.92 mL 23.85 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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