Selinexor (KPT-330)

目录号: A12582

CRM1 抑制剂

Selinexor (KPT-330)

Selinexor (KPT-330) Chemical Structure

CAS NO. 1393477-72-9

CRM1(XPO1)介导的核输出的KPT-330抑制剂在T细胞急性淋巴细胞白血病和急性骨髓性白血病的临床前模型中具有选择性的抗白血病活性。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 1,120.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CRM1(XPO1)介导的核输出的KPT-330抑制剂在T细胞急性淋巴细胞白血病和急性骨髓性白血病的临床前模型中具有选择性的抗白血病活性。
靶点信息
CRM1 (Cell-free assay)
In vitro (25°C) DMSO 78 mg/mL (175.94 mM)
Water Insoluble
Ethanol 36 mg/mL (81.21 mM)
In vivo 2% DMSO+40%PEG 300+5% Tween80 +ddH2O 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.56 mL 112.79 mL 225.58 mL
0.5 mM 4.51 mL 22.56 mL 45.12 mL
1 mM 2.26 mL 11.28 mL 22.56 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12582
作用机制 Inhibitor (抑制剂)
M. Wt 443.31
Formula C17H11F6N7O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1393477-72-9
Synonyms KPT330, KPT 330
SMILES C1=CN=C(C=N1)NNC(=O)/C=C\N2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

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