KPT 335
目录号: A16078
SINE 抑制剂
KPT 335 是一种口服生物利用度的选择性核输出抑制剂（SINE）。
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生物活性
| Discription | KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE). | |||||
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| Targets |
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| Cell Research |
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产品信息
| 目录号 | A16078 |
|---|---|
| 分子式 | C18H12F6N6O |
| 分子量 | 442.32 |
| CAS号 | 1392136-43-4 |
| SMILES | O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2 |
| 其他名称 | Verdinexor |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 83 mg/mL (187.65 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 10 mg/mL | ||
| In vivo | 5% DMSO+corn oil | 14 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.61 mL | 113.04 mL | 226.08 mL |
| 0.5 mM | 4.52 mL | 22.61 mL | 45.22 mL |
| 1 mM | 2.26 mL | 11.3 mL | 22.61 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1392136-43-4 | 1392136-43-4 供应商 | 1392136-43-4 花费 | 1392136-43-4 生产商 | 订购 1392136-43-4 | 1392136-43-4 代理商