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KPT 335

SINE 抑制剂

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产品目录号: A16078

库存状态:中国现货中国现货

产品名 目录号 价格 数量
KPT 335 5mg A16078-5
¥ 1,200.00
KPT 335 10mg A16078-10
¥ 1,800.00
KPT 335 50mg A16078-50
¥ 7,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).

KPT 335

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Chemical Information

目录号 A16078
Mechanism of action Inhibitor
分子量 442.32
化学分子式 C18H12F6N6O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1392136-43-4
Synonyms Verdinexor
SMILES code O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
化学名称 (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide

生物活性

Description
KPT 335 is an orally bioavailable Selective Inhibitor of Nuclear Export (SINE).
Targets
CRM1

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.61 mL 113.04 mL 226.08mL
0.5 mM 4.52 mL 22.61 mL 45.22 mL
1 mM 2.26 mL 11.3 mL 22.61 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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