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KPT-6566

目录号: A19126
prolyl isomerase PIN1 抑制剂
KPT-6566,一种强效的脯氨酸异构酶PIN1抑制剂,与PIN1的催化位点形成共价结合,选择性地抑制并降解PIN1。KPT-6566对PIN1 PPIase域的IC50为640纳摩尔,Ki为625.2纳摩尔。具有抗癌活性
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规格 价格 库存 数量
1mg
¥630.00
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2mg
¥980.00
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5mg
¥2,030.00
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10mg
¥3,150.00
现货
25mg
¥5,215.00
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50mg
¥7,385.00
现货
100mg
¥9,975.00
现货
10mM * 1mL in DMSO
¥1,960.00
现货
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生物活性
Discription KPT-6566, a potent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 of 640?nM and a Ki of 625.2 nM for PIN1 PPIase domain. Anti-cancer activity.
产品信息
目录号 A19126
分子式 C22H21NO5S2
分子量 443.54
CAS号 881487-77-0
SMILES O=C(O)CSC(C1=O)=C/C(C2=C1C=CC=C2)=N\S(=O)(C3=CC=C(C(C)(C)C)C=C3)=O
其他名称 KPT 6566; KPT6566
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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