KPT276
目录号: A16341
SINE/CRM1 抑制剂
KPT276，是KPT-185的类似物，是一种选择性的核输出抑制剂（SINE）和CRM1。
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生物活性
| Discription | KPT276, analog of KPT-185, is a selective inhibitor of nuclear export (SINE) and CRM1. |
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产品信息
| 目录号 | A16341 |
|---|---|
| 分子式 | C16H10F8N4O |
| 分子量 | 426.26 |
| CAS号 | 1421919-75-6 |
| SMILES | C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F |
| 其他名称 | KPT-276, KPT 276 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 17 mg/mL (39.87 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.46 mL | 117.3 mL | 234.6 mL |
| 0.5 mM | 4.69 mL | 23.46 mL | 46.92 mL |
| 1 mM | 2.35 mL | 11.73 mL | 23.46 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.69 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1421919-75-6 | 1421919-75-6 供应商 | 1421919-75-6 花费 | 1421919-75-6 生产商 | 订购 1421919-75-6 | 1421919-75-6 代理商