KRX-0402

目录号: A15459

DNA repair 抑制剂

KRX-0402

KRX-0402 Chemical Structure

CAS NO. 1000874-21-4

KRX-0402是一个小分子,专门设计用于阻断DNA修复蛋白MGMT。MGMT赋予了对某些烷基化剂(如替莫唑胺和BCNU)的抗性,后者通常用于治疗脑癌,黑色素瘤和非霍奇金淋巴瘤。

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,800.00
25 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

KRX-0402是一个小分子,专门设计用于阻断DNA修复蛋白MGMT。MGMT赋予了对某些烷基化剂(如替莫唑胺和BCNU)的抗性,后者通常用于治疗脑癌,黑色素瘤和非霍奇金淋巴瘤。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.45 mL 207.25 mL 414.51 mL
0.5 mM 8.29 mL 41.45 mL 82.9 mL
1 mM 4.15 mL 20.73 mL 41.45 mL
5 mM 0.83 mL 4.15 mL 8.29 mL

*The above data is based on the productmolecular weight 241.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15459
作用机制 Inhibitor (抑制剂)
M. Wt 241.25
Formula C12H11N5O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1000874-21-4
Synonyms O6-benzyl guanine, O6-BG
SMILES NC1=NC(OCC2=CC=CC=C2)=C3NC=NC3=N1

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