KS-176
目录号: A16195
BCRP 抑制剂
KS-176 是一种强效且选择性的乳腺癌耐药蛋白(BCRP)多药转运蛋白抑制剂,在 Pheo A 和 Hoechst 33342 测试中的 IC50 值分别为 0.59 和 1.39 uM。
Discription | KS-176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays respectively). |
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目录号 | A16195 |
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分子式 | C22H19N3O5 |
分子量 | 405.4 |
CAS号 | 1253452-78-6 |
SMILES | O=C(NC1=CC=C(CCO)C=C1)C2=CC=CC=C2NC(C3=CC=C([N+]([O-])=O)C=C3)=O |
其他名称 | KS176, KS 176 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 75 mg/mL (185 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (7.4 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.67 mL | 123.33 mL | 246.67 mL |
0.5 mM | 4.93 mL | 24.67 mL | 49.33 mL |
1 mM | 2.47 mL | 12.33 mL | 24.67 mL |
5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2