KU-0063794

目录号: A10505

mTOR Inhibitor

KU-0063794

KU-0063794 Chemical Structure

CAS NO. 938440-64-3

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
25 mg
¥ 1,500.00
50 mg
¥ 2,200.00
100 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).
Targets
mTORC1 (Cell-free assay) mTORC2 (Cell-free assay)
~10 nM~10 nM
In vitro (25°C) DMSO 16 mg/mL (34.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.41 mL 214.82 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10505
MECHANISM OF ACTION Inhibitor
M. Wt 465.5
Formula C25H31N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 938440-64-3
Synonyms KU0063794
SMILES C[C@@H]1CN(C[C@@H](O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5

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