KU-60019

Name: KU-60019
SKU: A10507
Price: 175 CNY
Rating: 5 (7 reviews)

目录号: A10507

ATM 抑制剂

7 篇发表文献

KU-60019 是一种效力强大且特异性的 ATM 抑制剂，其 IC50 为 6.3 nM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥455.00	现货
10mg	¥595.00	现货
25mg	¥1,295.00	现货
50mg	¥2,065.00	现货
100mg	¥3,465.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用KU-60019发表的7篇文献

Erika Nakatsuka, .et al. , Transl Oncol, 2024, Sep 12:50:102119 PMID: 39270525

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Yuri Tozaki, .et al. , Cancers (Basel), 2023, Jan 25;15(3):735 PMID: 36765693

Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458

Hegedus C, .et al. , Cancers (Basel), 2019, Dec 18;12(1) PMID: 31861350

Masaya Igase, .et al. , Mol Ther Oncolytics, 2019, vol 15 PMID: 31650025

CHENGHUA LOU, .et al. , Oncol Lett, 2016, Jul; 12(1): 295-300 PMID: 27347141

生物活性

Discription

KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10507
分子式	C30H33N3O5S
分子量	547.7
CAS号	925701-49-1, 925701-46-8
SMILES	C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 18 mg/mL (32.86 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.26 mL	91.29 mL	182.58 mL
0.5 mM	3.65 mL	18.26 mL	36.52 mL
1 mM	1.83 mL	9.13 mL	18.26 mL
5 mM	0.37 mL	1.83 mL	3.65 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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