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ATM 抑制剂

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产品目录号: A10507


产品名 目录号 价格 数量
KU-60019 10mg A10507-10
¥ 900.00
KU-60019 50mg A10507-50
¥ 3,000.00
KU-60019 100mg A10507-100
¥ 5,000.00
KU-60019 10mM * 1mL in DMSO A10507-10mM-D
¥ 1,080.00



KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 KU-60019 发表的文献 (1)
  • CHENGHUA LOU, .et al. Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells, Oncol Lett, 2016, Jul; 12(1): 295每300 PMID: 27347141

Chemical Information

目录号 A10507
Mechanism of action Inhibitor
分子量 547.7
化学分子式 C30H33N3O5S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 925701-49-1
Synonyms KU60019, KU-60019
SMILES code C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6
化学名称 (2R,6S)-2,6-Dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-4-morpholineacetamide


KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
ATM (Cell-free assay)
6.3 nM


Solubility (25°C)* In vitro DMSO 40 mg/mL (73.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol 30 mg/mL (54.77 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.26 mL 91.29 mL 182.58mL
0.5 mM 3.65 mL 18.26 mL 36.52 mL
1 mM 1.83 mL 9.13 mL 18.26 mL
5 mM 0.37 mL 1.83 mL 3.65 mL

*The above data is based on the productmolecular weight 547.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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