KW-2478

Name: KW-2478
SKU: A11195

目录号: A11195

HSP90 抑制剂

Product Citations (1)

KW-2478 Chemical Structure

CAS NO. 819812-04-9

KW-2478是一种靶向人热休克蛋白90（Hsp90）的药物，具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
5 mg	￥ 1,500.00
10 mg	￥ 2,500.00
50 mg	￥ 5,500.00
100 mg	￥ 9,000.00
10mM * 1mL in DMSO	￥ 2,310.00

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生物活性

KW-2478是一种靶向人热休克蛋白90（Hsp90）的药物，具有潜在的抗肿瘤活性。

靶点信息

HSP90
3.8 nM

溶解度 *

In vitro (25°C)	DMSO	114 mg/mL (198.37 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (5.22 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.4 mL	87.01 mL	174.02 mL
0.5 mM	3.48 mL	17.4 mL	34.8 mL
1 mM	1.74 mL	8.7 mL	17.4 mL
5 mM	0.35 mL	1.74 mL	3.48 mL

*The above data is based on the productmolecular weight 574.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11195
作用机制	Inhibitor (抑制剂)
M. Wt	574.66
Formula	C30H42N2O9
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	819812-04-9
Synonyms	KW2478
SMILES	CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O