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KW-2478

HSP90 抑制剂

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产品目录号: A11195

库存状态:中国现货中国现货

产品名 目录号 价格 数量
KW-2478 5mg A11195-5
¥ 1,500.00
KW-2478 10mg A11195-10
¥ 2,500.00
KW-2478 50mg A11195-50
¥ 5,500.00
KW-2478 100mg A11195-100
¥ 9,000.00
KW-2478 10mM * 1mL in DMSO A11195-10mM-D
¥ 2,310.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

KW-2478

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 KW-2478 发表的文献 (1)
  • Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107每113

Chemical Information

目录号 A11195
Mechanism of action Inhibitor
分子量 574.66
化学分子式 C30H42N2O9
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 819812-04-9
Synonyms KW2478
SMILES code CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O
化学名称 2-(2-ethyl-3,5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N,N-bis(2-methoxyethyl)acetamide

生物活性

Description

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

Targets
HSP90
3.8 nM

溶解性

Solubility (25°C) * In vitro DMSO 115 mg/mL (200.11 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (5.22 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.4 mL 87.01 mL 174.02mL
0.5 mM 3.48 mL 17.4 mL 34.8 mL
1 mM 1.74 mL 8.7 mL 17.4 mL
5 mM 0.35 mL 1.74 mL 3.48 mL

*The above data is based on the productmolecular weight 574.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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