L-685458
目录号: A15899
γ-secretase 抑制剂
L-685458 是一种特异性和高效的 A beta PP gamma-secretase 活性抑制剂，其 Ki 值为 17 nM。
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生物活性
| Discription | L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM. | |||||
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产品信息
| 目录号 | A15899 |
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| 分子式 | C39H52N4O6 |
| 分子量 | 672.85 |
| CAS号 | 292632-98-5 |
| SMILES | O=C(OC(C)(C)C)N[C@H]([C@H](O)C[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)CC3=CC=CC=C3 |
| 其他名称 | L685458, L 685458, L685,458 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 86 mg/mL (127.81 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 5 mg/mL (7.43 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.86 mL | 74.31 mL | 148.62 mL |
| 0.5 mM | 2.97 mL | 14.86 mL | 29.72 mL |
| 1 mM | 1.49 mL | 7.43 mL | 14.86 mL |
| 5 mM | 0.3 mL | 1.49 mL | 2.97 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 292632-98-5 | 292632-98-5 供应商 | 292632-98-5 花费 | 292632-98-5 生产商 | 订购 292632-98-5 | 292632-98-5 代理商