L-685458

目录号: A15899

γ-secretase inhibitor

L-685458 Chemical Structure

CAS NO. 292632-98-5

L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.

库存: 现货

规格 价格 数量
1 mg
¥ 1,500.00
2 mg
¥ 2,200.00
5 mg
¥ 4,750.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

L-685458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
Targets
Gamma-secretase
17 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.86 mL 74.31 mL 148.62 mL
0.5 mM 2.97 mL 14.86 mL 29.72 mL
1 mM 1.49 mL 7.43 mL 14.86 mL
5 mM 0.3 mL 1.49 mL 2.97 mL

*The above data is based on the productmolecular weight 672.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15899
MECHANISM OF ACTION Inhibitor
M. Wt 672.85
Formula C39H52N4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 292632-98-5
Synonyms L685458, L 685458, L685,458
SMILES O=C(OC(C)(C)C)N[C@H]([C@H](O)C[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)CC3=CC=CC=C3

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