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L189

DNA Ligase 抑制剂

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产品目录号: A15790

库存状态:中国现货中国现货

产品名 目录号 价格 数量
L189 10mg A15790-10
¥ 850.00
L189 25mg A15790-25
¥ 1,800.00
L189 50mg A15790-50
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

L189 is a novel human DNA ligase inhibitor, inhibits hLigI/III/IV with IC50 of 5/9/5 μM.

L189

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Chemical Information

目录号 A15790
Mechanism of action Inhibitor
分子量 246.29
化学分子式 C11H10N4OS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 64232-83-3
Synonyms L-189, L 189
SMILES code C1=CC=C(C=C1)C=NC2=C(NC(=S)NC2=O)N
化学名称 6-amino-5-(benzylideneamino)-2-sulfanylidene-1H-pyrimidin-4-one

生物活性

Description
L189 is a novel human DNA ligase inhibitor, inhibits hLigI/III/IV with IC50 of 5/9/5 μM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.6 mL 203.01 mL 406.03mL
0.5 mM 8.12 mL 40.6 mL 81.21 mL
1 mM 4.06 mL 20.3 mL 40.6 mL
5 mM 0.81 mL 4.06 mL 8.12 mL

*The above data is based on the productmolecular weight 246.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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