Lacnotuzumab (MCS110) is a humanized IgG1/?? monoclonal antibody that selectively targets colony-stimulating factor 1 (CSF-1), effectively blocking its interaction with the CSF-1 receptor (CSF-1R). This neutralization impedes CSF-1R activation, which is crucial in various cellular processes. Lacnotuzumab is primarily utilized in research focused on pigmented villonodular synovitis, providing valuable insights into the pathophysiology and potential therapeutic targets of this disease.
Lacnotuzumab (MCS110) is a humanized IgG1/?? monoclonal antibody that selectively targets colony-stimulating factor 1 (CSF-1), effectively blocking its interaction with the CSF-1 receptor (CSF-1R). This neutralization impedes CSF-1R activation, which is crucial in various cellular processes. Lacnotuzumab is primarily utilized in research focused on pigmented villonodular synovitis, providing valuable insights into the pathophysiology and potential therapeutic targets of this disease.
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