Lampalizumab (RG 7417) is a humanized monoclonal antibody designed to selectively target complement Factor D within the alternative complement pathway. By binding to an exosite, Lampalizumab effectively inhibits the access of Factor B to the active site, thereby modulating the pathway's activity. This antibody is primarily utilized in the study of age-related macular degeneration (AMD), providing a valuable tool for researchers exploring the pathophysiology and potential therapeutic interventions for this condition.
Lampalizumab (RG 7417) is a humanized monoclonal antibody designed to selectively target complement Factor D within the alternative complement pathway. By binding to an exosite, Lampalizumab effectively inhibits the access of Factor B to the active site, thereby modulating the pathway's activity. This antibody is primarily utilized in the study of age-related macular degeneration (AMD), providing a valuable tool for researchers exploring the pathophysiology and potential therapeutic interventions for this condition.
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