Lanabecestat

Name: Lanabecestat
SKU: A12282
Price: 700 CNY
Rating: 5 (288 reviews)

目录号: A12282

BACE1 抑制剂

Lanabecestat (AZD3293) 是一种效力强大的、高度渗透性的、口服活性的、能穿透血脑屏障的 BACE1 抑制剂，其 Ki 值为 0.4 nM。

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Grouped product items
规格	价格	库存
2mg	¥700.00	现货
5mg	¥1,470.00	现货
10mg	¥2,765.00	现货
50mg	¥7,525.00	现货
100mg	¥12,810.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Lanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12282
分子式	C26H28N4O
分子量	412.53
CAS号	1383982-64-6
SMILES	CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1
其他名称	AZD 3293, AZD-3293, AZD3293; LY3314814, LY-3314814, LY 3314814
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	80 mg/mL (193.92 mM)
	Water	Insoluble
	Ethanol	80 mg/mL (193.92 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.24 mL	121.2 mL	242.41 mL
0.5 mM	4.85 mL	24.24 mL	48.48 mL
1 mM	2.42 mL	12.12 mL	24.24 mL
5 mM	0.48 mL	2.42 mL	4.85 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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