Lanraplenib

Name: Lanraplenib
SKU: A12959

目录号: A12959

SYK inhibitor

Lanraplenib Chemical Structure

CAS NO. 1800046-95-0

Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.

库存：现货

规格	价格	数量
5 mg	￥ 1,130.00
10 mg	￥ 1,920.00
50 mg	￥ 5,650.00
100 mg	￥ 19,210.00

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产品详情

生物活性

Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.

溶解度 *

In vitro	DMSO	77 mg/mL (173.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.55 mL	112.74 mL	225.48 mL
0.5 mM	4.51 mL	22.55 mL	45.1 mL
1 mM	2.25 mL	11.27 mL	22.55 mL
5 mM	0.45 mL	2.25 mL	4.51 mL

*The above data is based on the productmolecular weight 443.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12959
作用机制	Inhibitor (抑制剂)
M. Wt	443.5
Formula	C23H25N9O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1800046-95-0
Synonyms	GS-9876, GS9876, GS 9876
SMILES	NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1