Lanraplenib

Name: Lanraplenib
SKU: A12959
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A12959

SYK 抑制剂

Lanraplenib (GS-9876) 是一种高度选择性且口服活性的 SYK 抑制剂（IC50=9.5 nM），目前正在开发中，用于治疗炎症性疾病。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥665.00	现货
10mg	¥1,155.00	现货
25mg	¥2,100.00	现货
50mg	¥3,115.00	现货
100mg	¥4,620.00	现货
*10mM 1mL in DMSO**	¥770.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12959
分子式	C23H25N9O
分子量	443.5
CAS号	1800046-95-0
SMILES	NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1
其他名称	GS-9876, GS9876, GS 9876
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (173.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.55 mL	112.74 mL	225.48 mL
0.5 mM	4.51 mL	22.55 mL	45.1 mL
1 mM	2.25 mL	11.27 mL	22.55 mL
5 mM	0.45 mL	2.25 mL	4.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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